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Blood 127:829838 Kato GJ, Steinberg MH, Gladwin MT (2017) Intravascular hemolysis and the pathophysiology of sickle cell disease

Both positive and negative mode ion polarity spectra were acquired with a mass range of m/z = 751125

Beta-glucuronidase, an enzyme produced by the gut microbiome, can reverse the reaction that the UGT enzymes did to make the estrogen metabolites more water-soluble

Aberrant glucose metabolism is a characteristic of cancer and the TME produces metabolic challenges to T cells, thus impairing the antitumor immune response [45]

At the top dose (675 mg/kg), relative kidney weights were slightly increased in males, urinary production was decreased, and there were variations in serum biochemistry, most of which were attributable to reduced water intake