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However, subsequent studies revealed that oridonin exhibits synergy effects with ACDs in various cancer cells, likely due to its anti-angiogenic effect and inhibition of the anti-apoptotic protein Bax-2 [52, 135]

If cells could survive in an atmosphere free of oxygen, most oxidative damage could be avoided

Xiao-Ai Jie-Du decoction and Tiansha Mixture are other promising formulations with documented anti-cancer properties [54, 55]

To test the anti-inflammatory effect of Liproxstatin-1 7- to 10-week-old WT and Gpx4 +/IEC mice were fed a Western diet (ssniff, TD88137) with 10% fish oil (ssniff supplementation, see Table S2) for 3 months ad libitum

GOx induces glucose starvation, impeding generation of NADPH through pentose phosphate pathway (PPP)