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Statements Data availability statement The original contributions presented in this study are included in this article/Supplementary material, further inquiries can be directed to the corresponding author

EPMA Journal 13 , 261284 (2022)

The role of NRF2/KEAP1 signaling pathway in cancer metabolism

30,58 These investigational therapies, as summarized in Table 3, reflect a shift toward mechanism-driven treatment in CLE, targeting underlying immune dysregulation to improve symptomatic control and patient outcomes