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Evidence indicates that the GM markedly elevates circulatory 25-hydroxyvitamin VitD levels by promoting the production of lactic acid and 7-dehydrocholesterol, therefore aiding skeletal calcium absorption (200)

In vitro biochemical analyses have shown that both monomeric and oligomeric -syn bind double-stranded DNA through electrostatic interactions, leading to conformational changes such as local bending, unwinding, or relaxation of supercoils ( Perspectives -synuclein and PARP-1 are both actively involved in the pathological process of PD, forming a self-perpetuating vicious cycle

Mice ( n = 3) anesthetized by intraperitoneal injection of 2.5% pentobarbital sodium (3.5 mL/kg) were scanned on a 3.0 T MR scanner equipped with a 50 mm 65 mm 8-channel phased-array mouse coil (Shanghai Chenguang Medical Technologies Co., Ltd., Shanghai, China)

Zhang S, Routledge MN