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The 20 mg dose matches the Itoh 2016 RCT that demonstrated cognitive improvements and the Harris 2013 trial that showed CRP reduction and mitochondrial marker improvement

Chen G, Yang F, Fan S, Jin H, Liao K, Li X et al (2022) Immunomodulatory roles of selenium nanoparticles: Novel arts for potential immunotherapy strategy development

Lipid droplets (LDs) are one of the major intracellular sites for the storage of triglycerides and cholesterol

In clinical practice, a notable 4060% of individuals diagnosed with depression demonstrate nonsuppression in the dexamethasone suppression test, indicative of compromised negative feedback mechanisms within the HPA axis (29)

doi: 10.1016/j.redox.2019.101328 238 NaguPSharmaVBehlTPathanAKAMehtaV