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The factors that trigger the development of valve myxomatous degeneration are still unknown, but aberrant TGFB signaling appears to initiate and perpetuate the valve pathology characteristic of this disease in the dog." Previously, different researchers had identified different chromosomes as possible regions for genes affecting mitral valve deterioration in MVD-affected dogs

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doi:10.1080/07315724.2020.1727380 [34] Mori H, Tack J, Suzuki H

Fecal DNA extraction and 16 S rRNA amplicon sequencing and sequencing analysis Fecal sample collection and genomic DNA extraction: Mouse fecal samples were collected from the large intestine during a sacrifice from both the long-term study in -carnitine-induced ApoE / mice and short-term study in the C57BL/6 J experimental mouse model