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On case by case basis, some insurance companies do reimburse for Hormone Replacement Therapy and Testosterone Replacement Therapy

The body readily converts cyanocobalamin to active forms through normal metabolic pathways, so bioavailability differences between B12 forms are minimal in individuals with intact conversion capacity

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Of course, people with a proper vitamin B12 deficiency will see more of a benefit, like improvement with less fatigue, nausea, and irritability

Its is a water soluble vitamin, so once your body takes in a certain amount, the rest is discarded through urine