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Shengjun Ji, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The peptide has a molecular weight of 1815.12 g/mol, contains a stabilizing disulfide bridge, and is classified as a modified hGH fragment

A fissure of the fibrous cap eliminates the barrier between the tissue factor rich in the lipid core and the coagulation factors in the bloodstream, which triggers a clotting reaction and leads to thrombosis in advanced atherosclerotic lesions (Figure 2C)

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