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The authors wish to thank the Smiling Dog Foundation for financial support of this project and to Bastyr University for its administration

A recent drug screening also identified a class I HDAC inhibitor, Vorinostat, as an inducer of ferroptosis in small cell lung cancer (SCLC) and isocitrate dehydrogenase ( IDH1/2 )-mutant brain tumors, suggesting an unique vulnerability that is regulated by histone or non-histone acetylation (84)