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Ltd., Hwaseong, Korea 7 Institute of Environmental Medicine, Seoul National University Medical Research Center, Seoul, Korea 8 Department of Occupational and Environmental Medicine, Hanyang University College of Medicine, Seoul, Korea Correspondence: Seungho Ryu, Department of Occupational and Environmental Medicine, Kangbuk Samsung Hospital, Samsung Main Building B2, 250, Taepyung-ro 2ga, Jung-gu, Seoul 04514, Korea, Tel: 82-2-2001-5137, Fax: 82-2-757-0436, E-mail: [email protected] Co-correspondence: Yoosoo Chang, Department of Occupational and Environmental Medicine, Kangbuk Samsung Hospital, Samsung Main Building B2, 250, Taepyung-ro 2ga, Jung-gu, Seoul 04514, Korea, Tel: 82-2-2001-5139, Fax: 82-2-757-0436, E-mail: [email protected] Received: July 12, 2022 Accepted: September 19, 2022 Copyright 2023 by the Korean Cancer Association This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

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it's an immersive journey into the heart of Nicaragua's cigar country