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2017;551(7679):247-250.[DOI] 90

Many studies have shown that certain biomaterials can provide three-dimensional structures suitable for stem cell growth to control undesirable migration, and can simultaneously be skilfully combined with biological factors or drugs that promote the differentiation of stem cells to NP cells, thereby promoting ECM secretion, inducing MSC differentiation to the NP cell phenotype, and accelerating IDD repair [91, 102, 103] (Fig

3.1 Neurotransmitter abnormalities Neurotransmitters play an important role in the regulation of neuronal activity, cognitive function and behavioral control