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Mills et al

Another putative cause of vitamin B-12 deficiency is the high-folatelow vitamin B-12 interaction, first suspected as the cause for observed relapse and exacerbation of the neurological symptoms in patients with pernicious anemia who were prescribed high oral doses of folic acid

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Older adults: Potentially up to 43% of older adults may be deficient in B12, depending on the definition used - that's due to not having enough IF to aid absorption