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One possibility is that the neurons in the BD COs are trying to recover from this inflexible capacity by upregulating their excitability to compensate, which leads to the aberrant electrophysiological patterns we see

The Endocrine Disruptor Bisphenol A (BPA) Exerts a Wide Range of Effects in Carcinogenesis and Response to Therapy

Diagnosis and differential diagnosis Diagnosis In HCC patients receiving molecular targeted therapy for more than one week or ICIs for four to twelve weeks, a diagnosis of DILI can be established if two or more of the following criteria are met: (1) Presence of symptoms such as fever, fatigue, nausea, or generalized discomfort, accompanied by abnormal liver biochemical markers (including ALT, AST, ALP, GGT, TBIL, albumin, etc.)

[DOI] [PMC free article] [PubMed] [Google Scholar] Yamamoto M, Yoshizaki K, Kishimoto T, Ito H

In general, the above described studies show that supplementation with Bacopa monnieri , acacia gum, acai seed extract, wolfberry preparation, milk fat globule and trigonelline was able to mitigate the ES-induced alterations in behavior