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Persistent exposure to senescence-derived cytokines elevates ROS production, disrupts redox homeostasis, and sensitizes neighboring neurons and glia to lipid peroxidationinduced membrane damage (Saul et al., 2022)

Los estudios mecansticos disponibles son predominantemente celulares y animales

Food Funct 2017;8:104351

A-lipoic acid improves abnormal behavior by mitigation of oxidative stress, inflammation, ferroptosis, and tauopathy in P301s tau transgenic mice

[20] For nutritional deficiency without intrinsic-factor loss, shorter courses-such as 30-100 mcg intramuscularly daily for five to ten days followed by 100-200 mcg monthly-are often sufficient