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The European Chemical Agency (ECHA) has granted full registration status to hesperidin, indicating its compliance with safety standards

In glaucoma, RGCs exhibit lower levels of BDNF and higher expression of its receptor, TrkB, which provides neuroprotection for RGCs

Egrifta is FDA-approved for HIV-associated lipodystrophy

Data availability All data generated or analyzed during this study are included in this published study and its supplementary information files

Disruption of this barrier, often resulting from microbial dysbiosis, facilitates the translocation of bacteria and their metabolites into the mucosa and bloodstream, triggering immune and inflammatory responses that can propagate to the brain and exacerbate neuroinflammation