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In contrast, similar experiments in breast cancer MCF7 cells revealed only modest effects on platinum sensitivity (Peklak-Scott et al, 2008), while partial GSTP1 knockdown in the adriamycin-resistant human colorectal cancer cell line M7609 increased sensitivity not only to the selection agent, but to cisplatin, melphalan and etoposide (Ban et al, 1996)

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158 Oral exposure to cylindrospermopsin leads to reduced gut bacterial phylum diversity, accompanied by increased Clostridioides difficile abundance and reduced beneficial flora like Roseburia , Akkermansia , and Bacteroides thetaiotaomicron ( B

Arrhythmia exacerbation, chest pain (unspecified), flushing, hypotension, myocardial infarction, and vasculitis have been observed during postmarketing experience

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