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Additionally, many patients with depression also experience other psychiatric disorders, which further increases the risk of development if effectively managed overdue

and since the schilling test is no longer available the exact cause of the low b12 which is not technically the same thing as pernicious anaemia not caused by diet is probably unknown so 1mg cyancobalamin will probably help someone who can produce some Intrinsic Factor that they can absorb enough from a oral supplement but just not from food but to presume it will help everyone is absurd

doi: 10.1038/s41575-024-01035-7

Human data are limited to observational studies correlating endogenous MOTs-C levels with metabolic outcomesno interventional human trials of exogenous MOTs-C have been published