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Similarly, redox-responsive carriers incorporating disulfide bridges (cleaved by elevated glutathione in activated microglia or neurons) liberate bacosides or quercetin exactly at sites of neuroinflammation, amplifying Nrf2 activation and neuroprotection while remaining inert during circulation (180)

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Exosomes play a crucial role in facilitating intercellular communication by transporting lipids, proteins, and various nucleic acids such as mRNAs, circular RNA, and miRNA (215)

After being digested and washed with phosphate-buffered saline (PBS), SH-SY5Y or microglia cells were further analyzed

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