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The oxidized form of thioredoxin is reduced directly by NADPH and thioredoxin reductase, whereas glutaredoxin is reduced by GSH using electrons donated by NADPH via glutathione reductase

Further phenotypic heterogeneity of CoQ10 deficiency associated with steroid resistant nephrotic syndrome and novel COQ2 and COQ6 variants

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Ascorbic acid is well known reducing agent, thus serves as a good antioxidant [18]

The nuclear receptor transcription factor Nurr1 orchestrates DA neuron maturation, functional regulation, and lifelong maintenance, with its expressioninitiating in the VM at embryonic day 10.5 (in mice) and persisting throughout adulthoodmediating perinatal stress response adaptation (Zetterstrm et al., 1996)