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Endocrinology (2002) 143:453643

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For decades, the solution was simply to drink more coffee or rely on chemical stimulants that borrow energy from tomorrow to get through today

In this study, myosteatosis was associated with poorer OS and PFS in patients treated with PD-1 inhibitor plus tyrosine kinase inhibitors, but showed a protective effect on PFS in those receiving PD-1 plus CTLA-4 blockade, potentially due to differences in immune cell composition and checkpoint expression within the TME [141]