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Intracellular lipid peroxide (LPO) detection To detect the intracellular LPO content, 143B cells were incubated with PBS, Ru(II)-OH, NP2, and NP4 (Ru 10 M) for 6 h

Similar findings were also observed in neuron-specific GCL knockdown mouse by Fernandez-Fernandez et al

Patients often notice a gentle glow after the first session, while deeper concerns such as melasma, sun spots, tanning, and long-standing dark patches fade gradually with repeated treatments

Enzymes that catalyze antioxidant reactions: Reduced glutathione (G-SH), a tripeptide-thiol (-glutamylcysteinylglycine) present in most cells, can chemically detoxify H 2 O 2 (Figure 13.5B)