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In wild type IDH cells, (D)-2HG is produced from hydroxyacidoxoacid transhydrogenase that converts -hydroxybutyrate to succinic semialdehyde while reducing 2KG to (D)-2HG [83]

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Microbial GGTs, covering the structurefunction relationship of the protein and their biotechnological significance, have been reviewed by The current review focuses mainly on bacterial GGTs with emphasis on their physiological significance, structural and molecular aspects, autoprocessing, and enzyme catalysis along with their relevance in biotechnology and biomedicine sectors

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