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In one study, it was observed that engineered extracellular vesicle-based nanoformulations (EVNs) target neuroinflammation by blocking peripheral inflammatory cell infiltration and promoting the Nrf2GPX4 pathway to suppress inflammation (173)

Glutaredoxins in thiol/disulfide exchange

Compared with the untreated plants, all As-treated seedlings exhibited As-induced growth inhibition in terms of plant height, shoot FW, and shoot DW, regardless of GSH application

AEs were hypertension (7), hemoglobinuria (6), headache (2), nausea and vomiting (2), bradycardia (2), allergic reaction (1) and acute renal failure (1), related to the hemolysis and DMSO

Choosing a mix of water- and lipid-soluble antioxidants ensures protection across different cellular compartments and enhances overall resilience of skin tissues