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In accordance, MCL-1 inhibitors have shown pre-clinical activity in AML 15,16 , and MCL-1 inhibition synergized with Venetoclax in AML models 17,18,19

Finally, in obese patients, increased renal tubular reabsorption produces salt retention, which worsens high blood pressure

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There were a few limitations in this study such as using only male rodents to prevent a possible compounding effect of female hormones