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IRP1 contains an iron-sulfur cluster that, when assembled under iron-replete conditions, converts the protein into cytosolic aconitate hydratase, preventing IRE binding [64]

Trp53 Fx/Fx mice ( a-b )

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Chlamydia pneumoniae and hyperlipidemia are co-risk factors for atherosclerosis: infection prior to induction of hyperlipidemia does not accelerate development of atherosclerotic lesions in C57BL/6J mice